# 3D-segmentation + different thresholding across different slices

**URL:** <https://discourse.slicer.org/t/3d-segmentation-different-thresholding-across-different-slices/16000>\
**Category:** Support\
**Tags:** segmentation\
**Created:** [February 15, 2021, 4:14pm UTC](https://discourse.slicer.org/t/3d-segmentation-different-thresholding-across-different-slices/16000 "2021-02-15T16:14:39Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![lekremer](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/lekremer/32/9145_2.png) [@lekremer](https://discourse.slicer.org/u/lekremer)\
**Post date:** [February 15, 2021, 4:14pm UTC](https://discourse.slicer.org/t/3d-segmentation-different-thresholding-across-different-slices/16000/1 "2021-02-15T16:14:39Z")

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hello,

I want to do a 3d volume of a structure (e.g. kidney) of an image volume, but I need to threshold across the kidney at different threshold intensities. unfortunately, the threshold applies to the 3d volume the same intensity across all slides. is there a way to do this in an efficient manner, versus making a different segmentation for each image slice?

thanks

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**Author:** ![lassoan](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/lassoan/32/13_2.png) [@lassoan](https://discourse.slicer.org/u/lassoan)\
**Post date:** [February 15, 2021, 6:40pm UTC](https://discourse.slicer.org/t/3d-segmentation-different-thresholding-across-different-slices/16000/2 "2021-02-15T18:40:05Z")

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Indeed, simple global thresholding only works well in a few special cases (such as bone segmentation in CT). That is why we added several other semi-automatic segmentation methods that rely on local intensity changes only. The most commonly used is [Grow from seeds](https://slicer.readthedocs.io/en/latest/user_guide/modules/segmenteditor.html#grow-from-seeds), but you can also try Local threshold, Fast marching, Watershed, or Flood filling methods (in [SegmentEditorExtraEffects extension](https://github.com/lassoan/SlicerSegmentEditorExtraEffects/#slicersegmenteditorextraeffects)).