# ADC values on a DWI scan

**URL:** <https://discourse.slicer.org/t/adc-values-on-a-dwi-scan/1352>\
**Category:** Support\
**Tags:** diffusion\
**Created:** [November 2, 2017, 3:17pm UTC](https://discourse.slicer.org/t/adc-values-on-a-dwi-scan/1352 "2017-11-02T15:17:36Z")\
**Posts on this page:** 12\
**Page:** 1

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**Author:** ![faraz1368](https://avatars.discourse-cdn.com/v4/letter/f/f4b2a3/32.png) [@faraz1368](https://discourse.slicer.org/u/faraz1368)\
**Post date:** [November 2, 2017, 3:17pm UTC](https://discourse.slicer.org/t/adc-values-on-a-dwi-scan/1352/1 "2017-11-02T15:17:36Z")

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Hi,  
I wanted to know if it is possible to load a DWI scan into slicer, draw a ROI and find the ADC values (in 10-6 mm2/s) (average and a distribution curve) corresponding to that ROI.

Thank you for your responses  
Faraz

Slicer version:4.9.0 (nightly)  
operating system: Windows 7

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**Author:** ![happyle](https://avatars.discourse-cdn.com/v4/letter/h/ec9cab/32.png) [@happyle](https://discourse.slicer.org/u/happyle)\
**Post date:** [November 2, 2017, 3:30pm UTC](https://discourse.slicer.org/t/adc-values-on-a-dwi-scan/1352/2 "2017-11-02T15:30:55Z")

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it can be done on Firevoxel([https://wp.nyu.edu/firevoxel/](https://wp.nyu.edu/firevoxel/)),i wonder if 3Dslicer can do this too:grin:

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**Author:** ![fedorov](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/fedorov/32/14_2.png) [@fedorov](https://discourse.slicer.org/u/fedorov)\
**Post date:** [November 2, 2017, 4:58pm UTC](https://discourse.slicer.org/t/adc-values-on-a-dwi-scan/1352/3 "2017-11-02T16:58:41Z")

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If your DWI data can be parsed as a MultiVolume from DICOM Browser (it must be in DICOM to try that), you can next try DWModeling module from the SlicerProstate extension to fit various models to the data: [https://www.slicer.org/wiki/Documentation/Nightly/Modules/DWModeling](https://www.slicer.org/wiki/Documentation/Nightly/Modules/DWModeling)

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**Author:** ![ihnorton](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/ihnorton/32/9_2.png) [@ihnorton](https://discourse.slicer.org/u/ihnorton)\
**Post date:** [November 2, 2017, 11:55pm UTC](https://discourse.slicer.org/t/adc-values-on-a-dwi-scan/1352/4 "2017-11-02T23:55:20Z")

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If you have raw DWI you can use DWIConverter to load, then SlicerDMRI `Diffusion Tensor Estimation` and `DiffusionScalarMaps` to calculate an ADC volume; then use Segment Editor to draw ROI and LabelStatistics to measure. I’m not sure if this workflow is in any tutorials but I’ll check and send a link or some screenshot instructions tomorrow.

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**Author:** ![lassoan](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/lassoan/32/13_2.png) [@lassoan](https://discourse.slicer.org/u/lassoan)\
**Post date:** [November 3, 2017, 4:11pm UTC](https://discourse.slicer.org/t/adc-values-on-a-dwi-scan/1352/5 "2017-11-03T16:11:48Z")

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Just a small addition to @ihnorton’s recommendation: in this workflow, it is easier to use `Segment Statistics` module instead of `Label Statistics` module. (`Label Statistics` module requires labelmap volume as input, so you would first need to export segmentation to a labelmap volume.)

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**Author:** ![happyle](https://avatars.discourse-cdn.com/v4/letter/h/ec9cab/32.png) [@happyle](https://discourse.slicer.org/u/happyle)\
**Post date:** [November 7, 2017, 9:38am UTC](https://discourse.slicer.org/t/adc-values-on-a-dwi-scan/1352/6 "2017-11-07T09:38:23Z")

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failed and still don’t know how to do ,looking forward to the screenshot:grin:

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**Author:** ![ihnorton](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/ihnorton/32/9_2.png) [@ihnorton](https://discourse.slicer.org/u/ihnorton)\
**Post date:** [November 7, 2017, 7:49pm UTC](https://discourse.slicer.org/t/adc-values-on-a-dwi-scan/1352/7 "2017-11-07T19:49:58Z")

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Ok, we don’t have a complete workflow tutorial for this, yet, but here are the steps and link to documentation for each step.

1. Please [download the latest Slicer nightly](http://download.slicer.org) and install SlicerDMRI extension: [Download](http://dmri.slicer.org/download/)
2. Please follow the [DTI tutorial](https://www.slicer.org/slicerWiki/index.php/Documentation/Nightly/Training#Slicer4_Diffusion_Tensor_Imaging_Tutorial) for instructions to load data and estimate a tensor volume from raw DWI data.
3. Around page 47 is scalar calculation, and you can instead follow the next screenshot to calculate Mean Diffusivity (ADC):

![image](https://us1.discourse-cdn.com/flex002/uploads/slicer/original/3X/4/1/412a35d08a20c47862ad421b46396c2e0a4abf21.png)

1. Then use the [Segment Editor](http://slicer.readthedocs.io/en/latest/user_guide/module_segmenteditor.html) to create regions of interest.

2. Then follow this video to use the Segment Statistics module as Andras suggested:

[![](https://img.youtube.com/vi/fM_rxfDTRi0/maxresdefault.jpg "Segment statistics - new module in 3D Slicer") ](https://www.youtube.com/watch?v=fM_rxfDTRi0)

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**Author:** ![Joejoe](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/joejoe/32/2288_2.png) [@Joejoe](https://discourse.slicer.org/u/Joejoe)\
**Post date:** [October 21, 2018, 2:17pm UTC](https://discourse.slicer.org/t/adc-values-on-a-dwi-scan/1352/8 "2018-10-21T14:17:19Z")

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How about DWI images of other organs, like the breasts. I have dwi data of breast with b values of 0, 800, 1400, 2000. Can I calculate the ADC value from the trace DICOM files in 3D slicer? or better, use a DKI model to obtain diffusity and kurtosis scalar map.

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**Author:** ![fedorov](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/fedorov/32/14_2.png) [@fedorov](https://discourse.slicer.org/u/fedorov)\
**Post date:** [October 21, 2018, 5:51pm UTC](https://discourse.slicer.org/t/adc-values-on-a-dwi-scan/1352/9 "2018-10-21T17:51:40Z")

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You can fit DWI data using the DWModeling module of the SlicerProstate extension.

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**Author:** ![Mgi](https://avatars.discourse-cdn.com/v4/letter/m/b19c9b/32.png) [@Mgi](https://discourse.slicer.org/u/Mgi)\
**Post date:** [April 21, 2021, 11:36pm UTC](https://discourse.slicer.org/t/adc-values-on-a-dwi-scan/1352/10 "2021-04-21T23:36:04Z")

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Hi @fedorov ! I am using the Slicer version 4.11.20200930 on Windows 10. I want to calculate the ADC values from breast DWI images. I used the DWModeling module but I can not see the results, Could you share to me a tutorial, please? or tell me How I can see the results?

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**Author:** ![fedorov](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/fedorov/32/14_2.png) [@fedorov](https://discourse.slicer.org/u/fedorov)\
**Post date:** [April 22, 2021, 3:11pm UTC](https://discourse.slicer.org/t/adc-values-on-a-dwi-scan/1352/11 "2021-04-22T15:11:57Z")

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The question from @Mgi is being discussed in a separate thread here: [Calculate the ADC for different b values in Breast DWI images](https://discourse.slicer.org/t/calculate-the-adc-for-different-b-values-in-breast-dwi-images/17241).

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**Author:** ![Mgi](https://avatars.discourse-cdn.com/v4/letter/m/b19c9b/32.png) [@Mgi](https://discourse.slicer.org/u/Mgi)\
**Post date:** [April 23, 2021, 9:09pm UTC](https://discourse.slicer.org/t/adc-values-on-a-dwi-scan/1352/12 "2021-04-23T21:09:35Z")

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Hi @Joejoe ! Could you solve this problem?