# Covariate Significance Testing - multiple covariate testing problem(s)

**URL:** <https://discourse.slicer.org/t/covariate-significance-testing-multiple-covariate-testing-problem-s/16036>\
**Category:** SlicerSALT\
**Created:** [February 17, 2021, 5:29pm UTC](https://discourse.slicer.org/t/covariate-significance-testing-multiple-covariate-testing-problem-s/16036 "2021-02-17T17:29:48Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![ikhsannk](https://avatars.discourse-cdn.com/v4/letter/i/e47774/32.png) [@ikhsannk](https://discourse.slicer.org/u/ikhsannk)\
**Post date:** [February 17, 2021, 5:29pm UTC](https://discourse.slicer.org/t/covariate-significance-testing-multiple-covariate-testing-problem-s/16036/1 "2021-02-17T17:29:48Z")

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Hello, my name is Ikhsan and I have some questions regarding multiple covariate testing on the Covariate Significance Testing module.

Before that, I have followed the tutorial using the example dataset (bump\*\*.vtk) provided and I got a positive result. I have also read some topics and discussions in this forum related to my following questions.

In my case, I would like to run a statistical shape analysis (group differences) on dentate nucleus and include age as a covariate. I have successfully performed and got the p-value from the group difference test between the controls and patients without any covariate. However, when I included another column (age) on my CSV file, it only showed the p-value for age and displayed no p-value difference in the controls vs patients.

I have tested my CSV file in the Shape Population Viewer and it functions properly. The picture below shows my screen capture of my shape analysis attempt; the p-value of controls vs patients, the p-value of age differences alone, and the p-value of both groups and age (the two images are the same file that I load twice to show the problem).

Could someone please give me suggestions on where I went wrong? Thank you in advance.

Regards,  
Ikhsan

 ![CST P-VALUE Group Only](https://us1.discourse-cdn.com/flex002/uploads/slicer/original/3X/2/4/240821778155b5696d254b2d7ed09c62ae753b67.png) ![CST P-VALUE Age Only](https://us1.discourse-cdn.com/flex002/uploads/slicer/original/3X/1/8/1810d4c914c81bf970edc7e2f0d75939e8b0fe1a.png) ![CST P-VALUE Group Age](https://us1.discourse-cdn.com/flex002/uploads/slicer/original/3X/a/5/a59413e079737f1592f194faeba21b6be7c119d2.png)