# DCE time series recognised as Scalar volume

**URL:** <https://discourse.slicer.org/t/dce-time-series-recognised-as-scalar-volume/33198>\
**Category:** Support\
**Created:** [December 4, 2023, 12:32pm UTC](https://discourse.slicer.org/t/dce-time-series-recognised-as-scalar-volume/33198 "2023-12-04T12:32:38Z")\
**Posts on this page:** 5\
**Page:** 1

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**Author:** ![winter](https://avatars.discourse-cdn.com/v4/letter/w/2bfe46/32.png) [@winter](https://discourse.slicer.org/u/winter)\
**Post date:** [December 4, 2023, 12:32pm UTC](https://discourse.slicer.org/t/dce-time-series-recognised-as-scalar-volume/33198/1 "2023-12-04T12:32:38Z")

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Operating system: Windows 10 Enterprise 64 bit  
Slicer version:5.6.0  
Expected behavior: load multiframe time series DCE data as multiframe object  
Actual behavior: recognised as scalar volume

Dear Communinty,

I want to analyse data coming from a time serie of images from a DCE experiment.  
The serie contains time serie of images throughout 9 minutes of imagin time in 3 image layers. When I load the DICOM data into 3DSlicer, the experiment is not recognised as multiframe object but as scalar volume (The images are then arranged firstly in the order of time and secondly in order of Frames). This is why it won’t be recognised in the MultiVolumeExplorer as an input multivolume.

Can someone help me solving the issue?

Thank you!

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**Author:** ![lassoan](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/lassoan/32/13_2.png) [@lassoan](https://discourse.slicer.org/u/lassoan)\
**Post date:** [July 31, 2024, 11:33am UTC](https://discourse.slicer.org/t/dce-time-series-recognised-as-scalar-volume/33198/2 "2024-07-31T11:33:20Z")

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This 4D DICOM image is saved in enhanced multi-frame MRI format, which is not supported by Slicer’s 4D DICOM importer. However, you can use [dcm2niix](https://github.com/rordenlab/dcm2niix) to create a 4D NRRD file that Slicer can load:

```txt
dcm2niix -e y -z y path/to/dicomfiles

```

When you drag-and-drop the .nhdr file into Slicer and the “Add data” window appears, choose `Sequence` in `Description` column.

You can then replay the time sequence using the sequence toolbar and display time-intensity plot using Sequences module:

 ![image](https://us1.discourse-cdn.com/flex002/uploads/slicer/original/3X/3/3/33efc149659cad74fc93b4b7a8436bf73140c151.png)

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<div class="post-metadata">

**Author:** ![winter](https://avatars.discourse-cdn.com/v4/letter/w/2bfe46/32.png) [@winter](https://discourse.slicer.org/u/winter)\
**Post date:** [August 2, 2024, 9:16am UTC](https://discourse.slicer.org/t/dce-time-series-recognised-as-scalar-volume/33198/3 "2024-08-02T09:16:15Z")

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Dear Andras,  
I am unfamiliar with dcm2niix. Can you please tell me more detailed how to install it (if needed), where I have to type “dcm2niix -e y -z y path/to/dicomfiles” in? Thank you.

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<div class="post-metadata">

**Author:** ![lassoan](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/lassoan/32/13_2.png) [@lassoan](https://discourse.slicer.org/u/lassoan)\
**Post date:** [August 2, 2024, 9:23am UTC](https://discourse.slicer.org/t/dce-time-series-recognised-as-scalar-volume/33198/4 "2024-08-02T09:23:38Z")

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If you wait a couple of days then a [fix](https://github.com/rordenlab/dcm2niix/pull/843) in dcm2niix will be integrated that will make Slicer be able to load DCE-MRI sequences from DICOM without typing commands.

If you dont want to wait then you can download dcm2niix and run the command I provided above in the terminal window of the operating system.

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<div class="post-metadata">

**Author:** ![winter](https://avatars.discourse-cdn.com/v4/letter/w/2bfe46/32.png) [@winter](https://discourse.slicer.org/u/winter)\
**Post date:** [February 4, 2025, 9:39am UTC](https://discourse.slicer.org/t/dce-time-series-recognised-as-scalar-volume/33198/5 "2025-02-04T09:39:34Z")

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Dear Andras!

I tried to open the DCE dataset in Slicer 5.8.0 by using “Diffusion-weighted DICOM Import (DCM2niixGUI)” plugin. This opens the dataset but it seems to contain only 1 timepoint. If I go to sequences, it still does not recognizes any sequence.  
What do I wrong? Can you help me please?

 ![DCE](https://us1.discourse-cdn.com/flex002/uploads/slicer/original/3X/e/b/eb507776b1a5ab641bcf96660522896a439adf76.png)