Expert automated registration

Rigid registration of these data sets work well, using SlicerElastix:

  • Prealign the volumes (for example, you can use 3 landmark points and SlicerIGT extension’s Fiducial Registration wizard module)
  • Define a ROI that contains the common region between the CT and MRI
  • Crop the CT and the MRI using this common ROI using Crop volume module (you will have a cropped MRI and cropped CT)
  • Apply bias field correction to the cropped MRI (slightly improves the end result)
  • Register the cropped CT with the cropped bias-corrected MRI using SlicerElastix, using “generic rigid (all)” preset

Deformable registration is challenging, maybe because of the large difference in rectal and bladder filling, but maybe further reducing the region of interest and tuning registration parameters could help.

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