# General Registration（pre CBCT+postCBCT）

**URL:** <https://discourse.slicer.org/t/general-registration-pre-cbct-postcbct/17412>\
**Category:** Support\
**Tags:** registration\
**Created:** [May 3, 2021, 9:42am UTC](https://discourse.slicer.org/t/general-registration-pre-cbct-postcbct/17412 "2021-05-03T09:42:06Z")\
**Posts on this page:** 3\
**Page:** 1

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**Author:** ![lili-yu22](https://avatars.discourse-cdn.com/v4/letter/l/dbc845/32.png) [@lili-yu22](https://discourse.slicer.org/u/lili-yu22)\
**Post date:** [May 3, 2021, 9:42am UTC](https://discourse.slicer.org/t/general-registration-pre-cbct-postcbct/17412/1 "2021-05-03T09:42:06Z")

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hi，  
i have a problem with BRANS  
i want to do do the registration between PreCBCT and ProCBCT of a patient’s skull  
Operating systerm:windows  
Slicer version:4.11.20210226  
Parameter set:General Registration  
percentage samples:0.05  
output settings:slicer liner transform  
Registration phases:Rigid(6DOF)  
masking option:ROI(the masked area is the skull base )  
after apply,the reasult is below:  
General Registration (BRAINS) standard output:  
Original Fixed image origin[-384, -384, -72.5, 0]  
Error while reading in imageC:/Users/13151/AppData/Local/Temp/Slicer/BIGBC\_vtkMRMLLabelMapVolumeNodeB.nrrd

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**Author:** ![lassoan](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/lassoan/32/13_2.png) [@lassoan](https://discourse.slicer.org/u/lassoan)\
**Post date:** [May 21, 2021, 6:47pm UTC](https://discourse.slicer.org/t/general-registration-pre-cbct-postcbct/17412/2 "2021-05-21T18:47:31Z")

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It seems that one of the masks are invalid (probably empty). If you are sure that the mask is correct then you can try SlicerElastix extension, too.

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**Author:** ![lili-yu22](https://avatars.discourse-cdn.com/v4/letter/l/dbc845/32.png) [@lili-yu22](https://discourse.slicer.org/u/lili-yu22)\
**Post date:** [May 24, 2021, 11:34pm UTC](https://discourse.slicer.org/t/general-registration-pre-cbct-postcbct/17412/3 "2021-05-24T23:34:45Z")

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thank you very much.