# 'Global' FW/FA Inquiry - whitematteranalysis

**URL:** <https://discourse.slicer.org/t/global-fw-fa-inquiry-whitematteranalysis/40989>\
**Category:** SlicerDMRI\
**Created:** [January 8, 2025, 1:28am UTC](https://discourse.slicer.org/t/global-fw-fa-inquiry-whitematteranalysis/40989 "2025-01-08T01:28:15Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![kvandeloo](https://avatars.discourse-cdn.com/v4/letter/k/a698b9/32.png) [@kvandeloo](https://discourse.slicer.org/u/kvandeloo)\
**Post date:** [January 8, 2025, 1:28am UTC](https://discourse.slicer.org/t/global-fw-fa-inquiry-whitematteranalysis/40989/1 "2025-01-08T01:28:15Z")

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I’m using whitematteranalysis for whole-brain tractography analysis ([Tutorial - whitematteranalysis 0.4.0 documentation](https://whitematteranalysis.readthedocs.io/en/latest/subject-specific-tractography-parcellation.html#)). Using this tutorial, I’m able to derive FA and FW from anatomical tracts and/or 800 fibre clusters as per the ORG white matter atlas. I’m interested in deriving ‘whole-brain’ or ‘global’ FW/FA - is it adequate to sum FA/FW values across the 800 clusters for each subject, or is there a better way to do this?

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**Author:** ![ljod](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/ljod/32/652_2.png) [@ljod](https://discourse.slicer.org/u/ljod)\
**Post date:** [May 20, 2025, 3:56pm UTC](https://discourse.slicer.org/t/global-fw-fa-inquiry-whitematteranalysis/40989/2 "2025-05-20T15:56:02Z")

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Apologies for the slow response. We have a script to correctly average values across fiber clusters taking into account the number of points within each fiber cluster. Its code is located here: [whitematteranalysis/bin/wm\_average\_tract\_measures.py at master · SlicerDMRI/whitematteranalysis · GitHub](https://github.com/SlicerDMRI/whitematteranalysis/blob/master/bin/wm_average_tract_measures.py)