# How to normalize MRI images using Slicer?

**URL:** <https://discourse.slicer.org/t/how-to-normalize-mri-images-using-slicer/14520>\
**Category:** Support\
**Tags:** segmentation\
**Created:** [November 10, 2020, 4:02pm UTC](https://discourse.slicer.org/t/how-to-normalize-mri-images-using-slicer/14520 "2020-11-10T16:02:40Z")\
**Posts on this page:** 3\
**Page:** 1

<div class="post-metadata">

**Author:** ![Eshani](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/eshani/32/8790_2.png) [@Eshani](https://discourse.slicer.org/u/Eshani)\
**Post date:** [November 10, 2020, 4:02pm UTC](https://discourse.slicer.org/t/how-to-normalize-mri-images-using-slicer/14520/1 "2020-11-10T16:02:40Z")

</div>

Hi! I am using the Slicer 4.10.2 version to segment only the eyeball in my MRI images. So, I want to know the simplest way of preprocessing/normalizing of brain MRI images as I don’t have any knowledge regarding python codes.

---

<div class="post-metadata">

**Author:** ![lassoan](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/lassoan/32/13_2.png) [@lassoan](https://discourse.slicer.org/u/lassoan)\
**Post date:** [November 10, 2020, 7:18pm UTC](https://discourse.slicer.org/t/how-to-normalize-mri-images-using-slicer/14520/2 "2020-11-10T19:18:46Z")

</div>

Probably you don’t need much pre-processing/normalizing to segment the eyeball. I would expect that by using [“Local threshold” effect](https://discourse.slicer.org/t/new-segment-editor-effect-local-threshold/9233) you can segment the eyeball with a few clicks (set a threshold range then Ctrl-click in the eyeball).

---

<div class="post-metadata">

**Author:** ![Eshani](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/eshani/32/8790_2.png) [@Eshani](https://discourse.slicer.org/u/Eshani)\
**Post date:** [November 11, 2020, 12:50pm UTC](https://discourse.slicer.org/t/how-to-normalize-mri-images-using-slicer/14520/3 "2020-11-11T12:50:48Z")

</div>

Thank you very much!