# How to perform US MRI/CT registration?

**URL:** <https://discourse.slicer.org/t/how-to-perform-us-mri-ct-registration/35776>\
**Category:** Support\
**Created:** [April 28, 2024, 1:59am UTC](https://discourse.slicer.org/t/how-to-perform-us-mri-ct-registration/35776 "2024-04-28T01:59:18Z")\
**Posts on this page:** 5\
**Page:** 1

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**Author:** ![jay1987](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/jay1987/32/16183_2.png) [@jay1987](https://discourse.slicer.org/u/jay1987)\
**Post date:** [April 28, 2024, 1:59am UTC](https://discourse.slicer.org/t/how-to-perform-us-mri-ct-registration/35776/1 "2024-04-28T01:59:18Z")

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I want to perform registration from US to CT or MRI. The ants, elastix, and brains algorithms can perform registration from 3D to 3D. But if I want to perform registration from 2D US to 3D CT/MRI, is there any way in Slicer? Or can it be achieved through code?

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**Author:** ![pieper](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/pieper/32/8_2.png) [@pieper](https://discourse.slicer.org/u/pieper)\
**Post date:** [April 29, 2024, 3:56pm UTC](https://discourse.slicer.org/t/how-to-perform-us-mri-ct-registration/35776/2 "2024-04-29T15:56:59Z")

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I don’t have a good solution for this registration task.

But I used your question as a test for the AI plugin to discourse. It would be interesting to know if people think the result is helpful.

> [@Semantic search for this forum](https://discourse.slicer.org/t/semantic-search-for-this-forum/34811/6):
>
> I also tried posting [this question](https://discourse.slicer.org/t/how-to-perform-us-mri-ct-registration/35776) and here’s what I got. These results are encouraging I think. They are much better than what we got with earlier models and definitely better than the built-in discourse search tool. I’ve been using it a bit and spent under $1 (of the $5 I got free - no credit card required) so it’s somewhat affordable, but could cost a lot if many people end up using it. [claude\_3\_opus\_bot](https://discourse.slicer.org/u/claude_3_opus_bot)Forum Helper [10m](https://discourse.slicer.org/t/untitled-ai-bot-pm/35806/2) Search Found 1 [result](https://discourse.slicer.org/search?q=registration+2d+ultrasound+3d+ct+mri) for ‘registration 2d ultrasound 3d…

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**Author:** ![cpinter](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/cpinter/32/7995_2.png) [@cpinter](https://discourse.slicer.org/u/cpinter)\
**Post date:** [April 30, 2024, 12:07pm UTC](https://discourse.slicer.org/t/how-to-perform-us-mri-ct-registration/35776/3 "2024-04-30T12:07:36Z")

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I think the AI answer is pretty good. I’m not an expert in 2D-3D segmentation, but would have answered something similar if I had considered myself the best person to answer (which I didn’t so passed the opportunity to other, smarter people).

Unfortunately there is no clear solution, or any finished project I’m aware of. Making a 3D volume from the slice is an idea that did crossed my mind, but I don’t think it would work. However, it’s just a hunch, based on my knowledge about the BRAINS and Elastix extensions, so it’s worth a try. What I think that means is making a “thicker” slice, maybe 3 or 5 adjacent slices of that US image, make sure the area out of the fan is masked out, and run the registration in the two modules I mention above.

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**Author:** ![LeidyMoraV](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/leidymorav/32/70144_2.png) [@LeidyMoraV](https://discourse.slicer.org/u/LeidyMoraV)\
**Post date:** [April 30, 2024, 3:40pm UTC](https://discourse.slicer.org/t/how-to-perform-us-mri-ct-registration/35776/4 "2024-04-30T15:40:00Z")

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Maybe this article with help you with some ideas:  
Behnami, D., Sedghi, A., Anas, E.M.A. _et al._ Model-based registration of preprocedure MR and intraprocedure US of the lumbar spine. _Int J CARS_ **12** , 973–982 (2017). [Model-based registration of preprocedure MR and intraprocedure US of the lumbar spine | International Journal of Computer Assisted Radiology and Surgery](https://doi.org/10.1007/s11548-017-1552-2)

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**Author:** ![Ontheroad123](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/ontheroad123/32/78731_2.png) [@Ontheroad123](https://discourse.slicer.org/u/Ontheroad123)\
**Post date:** [December 4, 2024, 12:20pm UTC](https://discourse.slicer.org/t/how-to-perform-us-mri-ct-registration/35776/5 "2024-12-04T12:20:54Z")

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I meet the same problem, US is arbitrarily section without pose information， do you have resolve this problem?