# Normalise segmentations to MNI space

**URL:** <https://discourse.slicer.org/t/normalise-segmentations-to-mni-space/23045>\
**Category:** Support\
**Created:** [April 20, 2022, 11:28am UTC](https://discourse.slicer.org/t/normalise-segmentations-to-mni-space/23045 "2022-04-20T11:28:08Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![Hamoun\_Rozati](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/hamoun_rozati/32/15046_2.png) [@Hamoun\_Rozati](https://discourse.slicer.org/u/Hamoun_Rozati)\
**Post date:** [April 20, 2022, 11:28am UTC](https://discourse.slicer.org/t/normalise-segmentations-to-mni-space/23045/1 "2022-04-20T11:28:09Z")

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Hello all. I have a couple hundred MRI scans of patients with brain metastases which have been segmented. I want to create a heat map of all the lesions. I can normalise the individual MRI scans to MNI space using SPM12, is there a way to also normalise the segmentations? I can then use MRIcron to create a heat map. Or if there are any other suggestions on how to create a heat map within 3Dslicer?

Many thanks for your help.

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**Author:** ![mau\_igna\_06](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/mau_igna_06/32/9056_2.png) [@mau\_igna\_06](https://discourse.slicer.org/u/mau_igna_06)\
**Post date:** [April 20, 2022, 12:23pm UTC](https://discourse.slicer.org/t/normalise-segmentations-to-mni-space/23045/2 "2022-04-20T12:23:16Z")

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> [@Hamoun\_Rozati](#):
>
> want to create a heat map of all the lesions. I can normalise the individual MRI scans to MNI space using SPM12, is there a way to also normalise the segmentations?

I think you may want to check this playlist:

[![](https://img.youtube.com/vi/2zcfYgdxhKM/maxresdefault.jpg "2. Registration: Image Spaces and Spatial Transformations (Reg E2)") ](https://www.youtube.com/watch?v=2zcfYgdxhKM)