# Refereces for Tractography ROI Seeding

**URL:** <https://discourse.slicer.org/t/refereces-for-tractography-roi-seeding/5550>\
**Category:** SlicerDMRI\
**Tags:** tractography\
**Created:** [January 29, 2019, 12:21am UTC](https://discourse.slicer.org/t/refereces-for-tractography-roi-seeding/5550 "2019-01-29T00:21:28Z")\
**Posts on this page:** 3\
**Page:** 1

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**Author:** ![sim.zanoni](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/sim.zanoni/32/2983_2.png) [@sim.zanoni](https://discourse.slicer.org/u/sim.zanoni)\
**Post date:** [January 29, 2019, 12:21am UTC](https://discourse.slicer.org/t/refereces-for-tractography-roi-seeding/5550/1 "2019-01-29T00:21:28Z")

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Dear Authors/Contributors,

I would be interested in using the Tractography ROI Seeding module provided as extension in Slicer (4.8.1). I started by reading the documentation ([https://www.slicer.org/wiki/Documentation/Nightly/Modules/TractographyLabelMapSeeding](https://www.slicer.org/wiki/Documentation/Nightly/Modules/TractographyLabelMapSeeding)), however I haven’t found any reference paper for a detailed description of the algorithm implemented in this module. Would you be so kind to provide me with this necessary information?

Thanks.

Best regards,  
Simone

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**Author:** ![ljod](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/ljod/32/652_2.png) [@ljod](https://discourse.slicer.org/u/ljod)\
**Post date:** [January 31, 2019, 5:28pm UTC](https://discourse.slicer.org/t/refereces-for-tractography-roi-seeding/5550/2 "2019-01-31T17:28:46Z")

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Hi Simone.  
It is second-order Runge-Kutta integration, also called the midpoint method.  
Additional related documentation can be found here:  
[http://dmri.slicer.org/](http://dmri.slicer.org/)  
Best regards,  
Lauren

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**Author:** ![sim.zanoni](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/sim.zanoni/32/2983_2.png) [@sim.zanoni](https://discourse.slicer.org/u/sim.zanoni)\
**Post date:** [February 1, 2019, 1:34am UTC](https://discourse.slicer.org/t/refereces-for-tractography-roi-seeding/5550/3 "2019-02-01T01:34:00Z")

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Hi Lauren,  
Thanks for giving me this information.

Best regards,  
Simone