# Registration MRI breast with segmentation

**URL:** <https://discourse.slicer.org/t/registration-mri-breast-with-segmentation/16703>\
**Category:** Support\
**Tags:** registration\
**Created:** [March 22, 2021, 10:46pm UTC](https://discourse.slicer.org/t/registration-mri-breast-with-segmentation/16703 "2021-03-22T22:46:03Z")\
**Posts on this page:** 4\
**Page:** 1

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**Author:** ![Mgi](https://avatars.discourse-cdn.com/v4/letter/m/b19c9b/32.png) [@Mgi](https://discourse.slicer.org/u/Mgi)\
**Post date:** [March 22, 2021, 10:46pm UTC](https://discourse.slicer.org/t/registration-mri-breast-with-segmentation/16703/1 "2021-03-22T22:46:03Z")

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Hi Everyone!

I am working with 3D slicer 4.11.2 version on windows. I want to register intra subject breast substraction mri images, where I made one ROI segmentation, with DWI b0 images. Could you tell me which is the better slicer module to make the registration including the segmented ROI.

I am a novice in registration field. Hope for any kind help or comment, thanks a lot!

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**Author:** ![lassoan](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/lassoan/32/13_2.png) [@lassoan](https://discourse.slicer.org/u/lassoan)\
**Post date:** [March 23, 2021, 5:10am UTC](https://discourse.slicer.org/t/registration-mri-breast-with-segmentation/16703/2 "2021-03-23T05:10:12Z")

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[This documentation page](https://slicer.readthedocs.io/en/latest/user_guide/registration.html) should help you getting started. If you can post a few screenshot and experience with some of the registration methods and can tell a bit more about your constraints (time, accuracy, robustness, availability of expert for semi-automatic methods, etc.) then we can give more specific advice.

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**Author:** ![Mgi](https://avatars.discourse-cdn.com/v4/letter/m/b19c9b/32.png) [@Mgi](https://discourse.slicer.org/u/Mgi)\
**Post date:** [March 23, 2021, 1:42pm UTC](https://discourse.slicer.org/t/registration-mri-breast-with-segmentation/16703/3 "2021-03-23T13:42:17Z")

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Thank you! @lassoan I’m going to explain more about what I want to do:  
Already made:

1. I generate 1 frame of the subtraction mri image from the dynamic images using Multivolume module
2. I segmented one ROI from the subtraction breast mri image using Segment editor module  
Now:
3. I want to register the subtraction mri image with the DWI b0 image (intrasubject), acquired in the same study
4. I want to use the segmentation made early (step 2) in the DWI b0 image (Then I need the registration process include the transformations to the segmented ROI)
5. I want to calculate the ADC for different b values in DWI images

Hope for any kind help or comment, thanks a lot!

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<div class="post-metadata">

**Author:** ![lassoan](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/lassoan/32/13_2.png) [@lassoan](https://discourse.slicer.org/u/lassoan)\
**Post date:** [March 24, 2021, 5:07pm UTC](https://discourse.slicer.org/t/registration-mri-breast-with-segmentation/16703/4 "2021-03-24T17:07:31Z")

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Registration for compensating minor displacements due to patient motion during an imaging session should be quite straightforward if there are some common features between the images. You can try SlicerElastix default registration presets.

The computed transform can be applied to any nodes, including segmentations.

> [@Mgi](#):
>
> I want to calculate the ADC for different b values in DWI images

If you need help with this then it is better to create a new topic; and keep this topic focused on registration.
