# Segmenting a part of the tissue (colon, pouch) with very similar intensity to nearby structures

**URL:** <https://discourse.slicer.org/t/segmenting-a-part-of-the-tissue-colon-pouch-with-very-similar-intensity-to-nearby-structures/42359>\
**Category:** Support\
**Created:** [March 29, 2025, 4:16am UTC](https://discourse.slicer.org/t/segmenting-a-part-of-the-tissue-colon-pouch-with-very-similar-intensity-to-nearby-structures/42359 "2025-03-29T04:16:04Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![drhuzaifa](https://avatars.discourse-cdn.com/v4/letter/d/5daacb/32.png) [@drhuzaifa](https://discourse.slicer.org/u/drhuzaifa)\
**Post date:** [March 29, 2025, 4:16am UTC](https://discourse.slicer.org/t/segmenting-a-part-of-the-tissue-colon-pouch-with-very-similar-intensity-to-nearby-structures/42359/1 "2025-03-29T04:16:04Z")

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I have CT scan of the abdomen, and am trying to segment a “part” of the colon (pouch) along with the staple line, and since the pouch signal intensity very resembles nearby tissue, and using threshold gives lot of noise, so how could we segment a twisted tissue (which does not have a very discrete boundary [if we use threshold], and twisted in 3D) easily?