# Steps for Glioma Perfusion (CBV) and Diffusion (ADC) Analysis

**URL:** <https://discourse.slicer.org/t/steps-for-glioma-perfusion-cbv-and-diffusion-adc-analysis/46880>\
**Category:** Community\
**Created:** [April 30, 2026, 5:53pm UTC](https://discourse.slicer.org/t/steps-for-glioma-perfusion-cbv-and-diffusion-adc-analysis/46880 "2026-04-30T17:53:11Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![Edvinas\_Chaleckas](https://sea2.discourse-cdn.com/flex002/user_avatar/discourse.slicer.org/edvinas_chaleckas/32/78686_2.png) [@Edvinas\_Chaleckas](https://discourse.slicer.org/u/Edvinas_Chaleckas)\
**Post date:** [April 30, 2026, 5:53pm UTC](https://discourse.slicer.org/t/steps-for-glioma-perfusion-cbv-and-diffusion-adc-analysis/46880/1 "2026-04-30T17:53:11Z")

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Hello,

I am a new 3D Slicer user and I am working on a project to analyze 3D glioma datasets. My goal is to calculate:

1. **Perfusion parameters** , specifically Cerebral Blood Volume ( **CBV** ).

2. **Diffusion parameters** , specifically the Apparent Diffusion Coefficient ( **ADC** ).

I have the multi-parametric MRI sequences (DCE/DSC and DWI) ready. Could someone guide me through the recommended workflow or suggest the best extensions/modules for these calculations? Specifically, I am looking for:

- The best module for DWI to ADC map conversion.

- The workflow for DSC/DCE perfusion analysis to obtain CBV maps.

- Any tips on segmenting the 3D glioma volume to extract average values from these maps.

Thank you for your help!