That option controls how the image is sampled when scaled for display: nearest neighbor / linear (see https://en.wikipedia.org/wiki/Image_scaling for details). There is nothing to save - what you see is still the original volume.
That option controls how the image is sampled when scaled for display: nearest neighbor / linear (see https://en.wikipedia.org/wiki/Image_scaling for details). There is nothing to save - what you see is still the original volume.