Best Tools for Segmenting Cartilage in the Knee

Greetings,

I am working on a project which requires segmenting articular cartilage in the knee joint (specifically the femoral and tibial cartilage) from an MRI. It is a challenge to segment soft tissue like cartilage because a) thresholding does not distinguish it from other surrounding tissues and b) the tissue is so small and thin that it is easy to make errors in manual or even semi-autonomous segmentation.

Does anyone have suggestions for the best tools 3D Slicer has for going about this task? The major goals are accuracy and reproducibility. Thanks!