Long delay after disk activity stops when loading very large data

I have noticed a delay between the end of the loading my large NRRD files (not compressed) and the appearance of slice views, which can be a minute or two (never really timed either). I always assumed those are overheads associated with generating MRML nodes etc. But I never tested with such large dataset, my large files are 10-20GB range. Yours is almost 400GB.