I am interested in using geometric morphometrics through the SlicerMorph to analyze shape differences in varanid lizard lungs. The lungs are complex but the main intrapulmonary airways are at the heart of the diversity of the structures and share some similarities. Attached here is a screenshot of an STL of these structures. I’ve done some geometric morphometrics on bones before, but how should I approach this strucuture? The size, shape, and position of the holes in the long tube is important and I’d like to capture the variation in these as they lead to secondary bronchi that carry unique airflow patterns. Would it be best to try and fill the holes and then measure the resulting filled flat surfaces that are where the holes used to be, or try and arrange the landmarks around the holes but not in them?
Thanks for your suggestions!