MRI intensity normalization


I am wondering how to apply “μ±3σ” normalization method in 3D slicer. I found a filter named “NormalizeImageFilter” which normalize an image by setting its mean to zero and variance to one. Can I modify this “NormalizeImageFilter” and turn it into “μ±3σ” normalization method.

I am also reading a paper written by Schwier_et_al.,2018, this paper mentions that “Basic normalization was performed by scaling and shifting the values of the whole image to a mean signal value of 300 and a standard deviation of 100”, is that “μ±3σ” normalization method?

TingtingTitle normalization