You need to select the transform next to “Active Transform” label, then scroll down to “Apply transform” section. You can harden a transform with less clicks in Data module: double-click on the transform icon in the transforms column and choose “Harden transform”.
The screenshot above indicates that there might be something wrong with the frames. Maybe there are some extra frames in the sequence that don’t belong there (sometimes localizer images got mixed into the 3D series). Check slice positions in the DICOM browser’s metadata viewer.