How to compare two sets of brain MRI images and give diff color in the different parts?

Operating system: Window
Slicer version: 4.8.1
Expected behavior:
I would like to see the difference with red color
after comparsion of the two sets of MRI data

Actual behavior:
4.8.1 is not loading after I click, it is automatically deactivates and does nothing.

Please follow these instructions: