Howto find the largest empty circle or Maximum Inscribed Circle amid a set of points, and in an enclosing polygon by python code?
Someone here 
has used OpenCV to do it in the 2D plane. If you don’t use OpenCV, what should you do in the 3D space?
Find largest circle that fits within a set of points given a starting point (numpy)
Our is a very hard computational geometry problem. Probably there are easier ways to achieve what your need. What is your end goal?