Other than manually filling the holes with “Paint” and removing the easy islands with “Islands”.
In this picture you can see the part above the nose (sorry not for using medical terms, I’m not from that field) and in the eye socket. They have a few holes. The actual bone is continuous, so I assume that issue is that the scan is not perfect. I tried playing around with smoothing (fill holes) but I’m looking for something more automatic, if exists. In addition, I want to remove the spine.
Previously, when I wanted to isolate the brain, it was pretty easy with Overview | 3D Slicer segmentation recipes . And when I had an MRI, I was able to get a really good image of just the brain using freesurfer’s recon-all
(and even with 3D slicer using SlicerSwissSkullStripper, although with some more manual fixing). Does something somewhat automatic exit for a skull CT?