Do you have a debug-mode build? It would be awesome if you could track this down. I would suspect that your mouse driver generates a mouse event between pressing and releasing the button, even if you don’t physically move the mouse (or maybe you move it by 0.00001mm) and that confuses the click detection logic here: Slicer/Libs/MRML/DisplayableManager/vtkMRMLViewInteractorStyle.cxx at main · Slicer/Slicer · GitHub. If indeed this is the problem then it could be fixed by checking how much the mouse was moved instead of just detecting that a mouse move event was fired.
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