RT STRUCT available. Would like to try a different segmentation on the CT images.

Operating system:
Edition Windows 10 Enterprise
Version 20H2
OS build 19042.1288
Experience Windows Feature Experience Pack 120.2212.3920.0
Processor: Intel(R) Core™ i5-10310U CPU @ 1.70GHz 2.21 GHz
System type: 64-bit operating system, x64-based processor

Slicer version:4.11.20210226 r29738 / 7a593c8
Expected behavior: I have head and neck cancer PET/CT dicom images from TCIA(The Cancer Imaging Archive)(298 patient images). The images are manually segmented. The RT struct is also available. Now I would like to try a different segmentation method on these images. I loaded RT STRUCT and PET/CT images and could figure out the GTV needed(BY hiding all other segmented regions). (There are many different ROIs segmented in the RTSTRUCT, but I need only GTVs). The problem is I am unable to use ‘segment editor’ when the RTSTRUCT is loaded. If I load the CT images alone, I have trouble identifying the GTV for segmentation. Is there a way to do thiS? I am a new 3D slicer user
Also, could you please advice me on, once segmented how to import these images to Pyradiomics for feature extraction?. I am trying to verify feature stability across different segmentation methods.
Many thanks in advance.

It would be helpful to hear what it means exactly that you are unable to use Segment Editor. I guess it says that you cannot edit the segmentation because the master representation is not labelmap. Is this correct?

In any case, in order to edit the structure set, I would

  1. Clone the segmentation in the Data module to preserve the original data for the session
  2. Go to Segmentations module, select the cloned node, then in the Representations section, in the line of Binary labelmap click Make master
  3. Go to Segment Editor and select the cloned segmentation, which you could now edit

Thanks for your response.
What you said is correct. I can’t find it as a binary label map. All I can find is planar contour. When I tried to create a binary label map from RTstruct, 3d slicer was not responding. Maybe I did a mistake there. When I select segment editor,
the Segmentation appears as ‘RTSTRUCT’ and Master Volume as ‘CT IMAGES’.
I will try what you suggested.



Please try with the latest Slicer Preview Release. After clicking “Create” for binary labelmap, be patient, conversion may take a while if you have many segments or your computer is low on memory.

Which TCIA data set is this?

The link to TCIA which has the head and neck cancer dataset -https://wiki.cancerimagingarchive.net/display/Public/Head-Neck-PET-CT
Thanks for your response. I was trying to follow what @cpinter suggested. But in the segment editor module, I am unable to find the cloned GTV. Could you please suggest on where can I find it?
What I could see was the below snippet when I tried to change ‘Master Volume’ from CT images to GTV. Is this needed?


Thank you!

Just downloaded the latest slicer preview release. But everything seems so slow and not working as in the stable version(it remains stuck). Close button seems to not appear in some cases. Any suggestions would be highly appreciated. Thanks!

Which data set you have problem with exactly? Can you tell the patient ID or study ID?

I’ve tested loading a few TCIA Head-Neck-PET-CT data sets, editing the structure sets and exporting the modified segment to DICOM and it all worked without issues, using latest Slicer Preview Release.

I don’t see any significant time difference between Slicer Preview Release and latest Slicer Stable Release when loading or editing segments.

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Thank you very much @lassoan for the video shared. I’m sure it will be of great help to me.
I will try again on the preview release.
As I have manually segmented images, I would like to try a different segmentation on the images, for eg: Otsu method. Do I have to clone the segment as Csaba mentioned before to try another segmentation method, to segment only the GTV? May I know how can I do that? And later I want to extract features from this.

This is the screen I see:


Thanks in advance

I would not use thresholding for segmentation, but Otsu method is available in the Threshold effect in Segment Editor.

You don’t need to clone, only if it makes your workflow easier. I recommend that you try all the things we suggeted, take a look at the Segment Editor effects and documentation (here and here), as well as the tutorials, and find the tools that fit your exact needs.

Thank you very much @cpinter and @lassoan .
I will try all the things you suggested and will see how it works. Thanks again.

In continuation to the question I asked previously, I have ~300 PET/CT images of head and neck cancer patients got from TCIA with its RTSTRUCT. The region of interest is different in each case eg: GTV, GTV_67.5Gy, GTV_70Gy. I wish to extract features from these ROIs(from manually segmented images) and also from the ROIs obtained by trying a different segmentation method on these images(both PET and CT). Is there a way to automate this task using Python script or so? It would have been a time saver. I found something like this here[Is there a way to build a macro/script out of segment editor steps? - #5 by pieper]
Thanks

Yes, all the steps that you perform in the GUI can be automated using Python scripting. The Slicer script repository is a good starting point but if you cannot find an example for anything that you would like to do then you can search this forum and ask us here, too.