So a ‘fun’ bug I noticed is that Slicer has trouble opening on non-primary monitors. I believe it is closely related to this issue, or some variation of it. It’s not you. It’s OpenGL.
An experiment to verify this is to unplug the second monitor or any other non-primary monitor, open Slicer, and see if it works. You may have to try moving it if it’s starting off-screen.
Cheers.