Hello, I am interested in doing perfusion analysis on dynamic contrast enhanced MRI images using Slicer. I see that there are two older extensions which allow this, PkModeling and DSCMRIAnalysis, both of which are CLI modules and both of which expect MultiVolumes as input. Using a recent Slicer 5.1 preview, I still have the option to load these series as MultiVolumes using the Advanced options in the DICOM browser, but my issue is that I want to do a rigid registration step before running the analysis. Sequence Registration is an easy solution for this and works well as long as I provide inputs in a Volume Sequence rather than a MultiVolume. I know that MultiVolumes and Sequences are conceptually quite similar and I think that converting between the two should be pretty easy, but I haven’t found an existing method for this. Can anyone point me in the right direction?
I also considered trying to update the DSCMRIAnalysis extension to take Volume Sequences as input instead of MultiVolumes, but the extension is a CLI module and I think might require getting into building Slicer and compiling from source and I think that will likely take more time and learning than I have available. A more feasible path for me seems to be to figure out how to convert a Sequence to a MultiVolume and then feed the existing CLI extension the input it expects.
My workflow would then be to load the perfusion images as a Volume Sequence, register using Sequence Registration, convert to MultiVolume, and run DSCMRIAnalysis.