Discontinuous ROI for radiomics

Hello, this is rather a general question regarding the functioning of the algorithm.

I have some ROIs that I use to extract image pixel intensity from images and would like to re-use these ROIs in feature detection. However, the ROIs are discontinuous (meaning that the a specific tissue is marked on different places in the scan, without there being connection between those tissues).

The radiomics program (at least pyradiomics) does produce a csv when using this ROI.

Will the output be anyhow affected by the discontinuity, i mean does the ROI border affect the feature recognition somehow?

Thanks in advance for the answer,