Getting HU values from one ROI applied to two different images

Hi all, is there a way to extract ROI values as arrays by using the same ROI on different images?
Suppose I want to register two CT scan in two different timepoints, I’d like to draw a ROI and then having the HU values as array with coordinates of image 1 and image 2. I read about the command slicer.util. arrayFromVolume but I’m not sure it’s the same case as mine.

Thank you!

Be sure to resample the data to the same pixel space (e.g. using the Resample Image (BRAINS) module) before doing array-level access to the pixel data.