Masking/segmentations disappearing issue

When I am segmenting, sometimes it will disappear on me. I can see it in the 3D area but not in any of slices. Sometimes, this will happen after I apply thresholding, and other times, it appears to occur randomly. Is there a setting or method to resolve this? Thank you!

Can you describe the circumstances that lead to the segment not being visible?

Perhaps you are seeing the same thing as this issue: Segment disappears after threshold effect preview; two widgets · Issue #6874 · Slicer/Slicer · GitHub