If anyone is wondering how 3D Slicer runs on a Surface Studio… It is just awesome! I had a chance to try it in a Microsoft Store (it helped that Slicer installation does not require administrator access anymore).
Thanks to recent improvements by @Sunderlandkyl, drawing with the surface pen is very smooth. The programmable wheel controller is very handy, too (I just added a prev/next slice action but any other shortcuts can be added).
If you don’t find keyboard shortcuts for any specific action you would like to assign to the dial then you can ask for advice here. You can always create new keyboard shortcuts to any Slicer functions as described here.