4D NifTi flipped and rotated about 90-deg

Hi everyone,

Whilst working with some NifTi files, all regular 3DNifti’s seem to match between my application and 3D-Slicer. However, I noticed that the 4D NifTi file I’m working with seems to be flipped in 3D-Slicer rather awkwardly (flipped + rotated). It’s worth mentioning that I was curious and I tried the same 4D NifTi in ITK-SNAP and it did line up with mine (albeit reversed coordinate system). Any idea why this is the case?

Regular Nifti comparison with 3D-Slicer

  • next is 3D slicer

Here is another regular comparison.

and another

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  • here is what ITK-SNAP produced, which is a lot similar to mine.