Error In total Segmentor macOS

Command ‘[’/Applications/Slicer.app/Contents/bin/../bin/PythonSlicer’, ‘/Applications/Slicer.app/Contents/lib/Python/bin/TotalSegmentator’, ‘-i’, ‘/private/var/folders/3n/nb74wlx17txbbdx1b3cjlwym0000gn/T/Slicer-gabriellunardiaranha/__SlicerTemp__2026-05-13_20+07+54.798/total-segmentator-input.nii’, ‘-o’, ‘/private/var/folders/3n/nb74wlx17txbbdx1b3cjlwym0000gn/T/Slicer-gabriellunardiaranha/__SlicerTemp__2026-05-13_20+07+54.798/segmentation’, ‘–device’, ‘cpu’, ‘–ml’, ‘–task’, ‘total’]’ returned non-zero exit status 1.


I’m trying to use Total Segmentor 3D Slicer 10.0 without success. I’ve already updated Python, NuNet, and everything else available in other topics. Thanks.

The problem was fixed recently. You need to install Slicer from scratch (remove or rename your current Slicer and install Slicer again) to start from a clean, tested state. Once you installed Slicer, you only need to install TotalSegmentator, then load an image (e.g., CTChest sample data) and it will all work (first time it takes about 5-10 minutes to install all required Python packages).