Operating system: Microsoft Windows 7 Enterprise Slicer version: Slicer 4.7.0 nightly build Expected behavior: Quantitative analysis of DCE MRI and measuring parameters like K trans and fractional value Actual behavior: Is there a way to do the quantitative analysis of DCE MRI of pancreatic tumor…

Hi Andrey, This is the tutorial I created for my research group. I hope it is helpful to others! Note I sub-linked a tutorial originally made by you that I found to really help also: PKModeling Tutorial Best, Madeline

Hello @kirezgik , (cc: @fedorov , @mschwier ) The issue is probably not in the PK Modeling module, but in the multivolume loading of Bruker data - specifically in recognition of the frametime. I will probably be working on correcting this during Project Week in June. I do not have your problematic orig…

Hi, I am not a developer myself, so I`d appreciate your help for that. @speled I just shared the original data with you. Thanks, Ezgi

@kirezgik (cc: @fedorov ) After you load the multivolume data, and save it (e.g. as .nhdr and .raw.gz) look at this field: MultiVolume.FrameLabels:=0.0,9074472.1875,18148944.375,27223416.5625,… This is a list of 90 values, and here it looks like the frametime is 9074472.1875 milliseconds, i.e. 151…

@speled the issue of temporal resolution has already been discussed - see this post: How to analyze DCE-MRI data - #23 by kirezgik . That did not help. [image] kirezgik: The temporal resolution will be the TR x the number of phase encoding repetitions. (You’ll have to check the TR for each indiv…

@kirezgik , @fedorov - so what is the problem? PK Modeling works for me with this data set. What does not work is the “Output Fitted Data 4D” feature.

[image] speled: PK Modeling works for me with this data set. I did not realize this was the case. What AIF did you use?

Hi – sorry I was not aware that the frame time issue had been figured out (since it was not brought up when we discussed Andrew and Jihun’s mouse data). Attached is the AIF label map that I used – voxels found using an automated algorithm applied to an artery. Best Sharon

Dear Dr Fedorov, Hello again! I am using pkModeling module on a liver tumor analysis project. I have a question, that on Huang2014 , it says pkModeling(BWH-3DSlicer) is using Tofts model. The paper was published 4 years ago. I would like to make sure whether there is a upgraded model (for example…

Tiger, we did not add any new models to PkModeling since the Huang2014 paper.

Dear Dr Fedorov, Since there is an option of computing fpv(i.e vp) with 3-parameter model, [%E5%9B%BE%E7%89%871] I assume you are using extended Tofts model, not Kety model [%E5%9B%BE%E7%89%872] because extended Tofts model contains 3 parameters Ktrans, vp and ve, and Kety model only contains 2…

How to analyze DCE-MRI data

Support

ThymusTheTrain October 21, 2023, 10:17pm 63

I tried following the tutorial linked in the OP, but after I load the test data I am unable to select anything for the Input Multivolume. I am using Slicer 5.

Could someone please guide me on how to properly load the data?

Topic		Replies	Views
DCE analysis - Ktrans is calculated only in a few small points Support dce	1	934	July 6, 2018
How to change the different flip angle volume into multivolume? Support	6	476	November 25, 2018
How to analyse CT time sequence data of lungs? Support	6	776	December 28, 2019
ERROR with DCE MRI loading in DICOM Browser Support	44	4598	September 13, 2017
Convert between MultiVolume and Volume Sequence? Support	21	1802	November 15, 2023

How to analyze DCE-MRI data

Related topics